2018 Symposium Agenda

Infectious Disease Research Talks 2018 Symposium: Metabolism of Infectious Diseases, Defining Relationships for Solutions Logo

Jun 12, 2018 (Tuesday)

Opening Session
4 p.m. Registration opens, packet pickup (Lory Student Center Ballroom C)
5 p.m. Welcome and opening remarks -Dr. Mark Stetter, Dean of the College of Veterinary Medicine & Biomedical Sciences, CSU
5:15 – 6:15 p.m. – Keynote Address: “Using the tools of systems biology to dissect the immune system” – Dr. Alan Aderem (Professor and President Emeritus, Center for Infectious Disease Research, Seattle, WA)

6:15 – 7:15 p.m. – Opening reception with cocktails, appetizers (Lory Student Center Ballroom D)

Jun 13, 2018 (Wednesday)

7 – 8 a.m. Networking and Coffee

Session 1. We Should Talk – Immunometabolism… from protection to pathology
8 – 8:30 a.m. Plenary Presentation: “(m)TORching metabolism in macrophages” – Thomas Weichhart, PhD, Medical University of Vienna
8:30 – 8:50 a.m. Abstract Selected Presentation: “Indoleamine 2,3, dioxygenase mediated modulation of immune responses to Mycobacterium tuberculosis: a target for host-directed therapeutics”-  Deepak Kaushal, PhD, Tulane University
8:50 – 9:10 a.m. Abstract Selected Presentation: “Francisella tularensis phospholipids utilize unique very long chain acyl motifs to manipulate host fatty acid metabolism” –  Benjamin Schwarz, PhD, Rocky Mountain Laboratories, NIH
9:10 – 9:40 a.m. Plenary Presentation: “Multi-omics approach to characterize metabolic reprogramming of innate immune responses in HIV infection” – Edana Cassol, PhD, Carleton University

9:40 – 10:10 a.m. Morning coffee break

Session 2. Building a Home – Pathogen manipulation of host metabolism
10:10 – 10:40 a.m. Plenary Presentation: “The pros and cons of host lipids during flavivirus replication” – Jason Mackenzie, PhD, University of Melbourne
10:40 – 11 a.m. Abstract Selected Presentation: “Pathogen manipulation of host metabolism: A common strategy for immune evasion” – Eric Harvill, PhD, University of Georgia
11 – 11:20 a.m. Abstract Selected Presentation:“MALDI FT-ICR mass spectrometry imaging reveals dysregulated lipid and small molecule metabolites in tissues harvested from mice infected with a bacterial or viral pathogens”  – Lisa Cazares, PhD, USAMRIID
11:20 – 11:50 a.m. Plenary Presentation: “Modulation of host metabolism by the intracellular pathogen Mycobacterium leprae: implications in leprosy pathogenesis” – Cristina Pessolani, PhD, Owsaldo Cruz Foundation (FIOCRUZ)

11:50 a.m. – 1:20 p.m. Lunch (Lory Student Center Ballroom C)
Presentation: “Reinventing the Metabolomics Untargeted Workflow with the Thermo Scientific™ Orbitrap ID-X™ Tribrid™ Mass Spectrometer” – Timothy E. Johnson, Thermo Fisher Scientific

Session 3. Not Lost in Translation – Targeting metabolism for therapeutics and biomarkers
1:20 – 1:50 p.m. Plenary Presentation: “Application of Metabolomics to Advance Understanding of Drug Action” – Kathleen Stringer, PharmD, University of Michigan
1:50 – 2:10 p.m. Abstract Selected Presentation: “Analysis of the Metabolic Pathways Affected during Cannabinoid Receptor Activation and Its Impact on Alphavirus Replication” – J. Jordan Steel, PhD,  Colorado State University-Pueblo
2:10 – 2:30 p.m. Abstract Selected Presentation: “Viral infection induces metabolic reprogramming in human respiratory cells: a host target with therapeutic potential” – Heather Smallwood, PhD, University of Tennessee Health Science Center
2:30 – 3 p.m. Plenary Presentation: “Trehalose metabolism of hypoxia induce quiescent state in Mycobacterium tuberculosis” – Hyungijn Eoh, DVM, PhD, University of Southern California

3 – 3:30 p.m.  Afternoon coffee break

Student/Post Doctoral Presentations
3:30 – 3:45 p.m. Student Presentation: “Novel metabolomic biomarkers of early-life “infections and growth: models of environmental enteropathy and field validation” – Natasa Giallourou, PhD,  Imperial College, London, UK
3:45 – 4 p.m. Student Presentation: “The effect of synthetic cystic fibrosis sputum media on Pseudomonas aeruginosa secondary metabolism” – Rachel Neve, University of Colorado-Denver
4 – 4:15 p.m. Student Presentation: “Antibacterial and antiviral immune responses are associated with differential reprogramming of mitochondrial function in mouse bone marrow derived macrophages” – Duale Ahmed, Carleton University, Canada
4:15 – 4:30 p.m. Student Presentation: “Role of 2-Alkyl-4-quinolones in Pseudomonas aeruginosa pathogenesis” – Luke Brewer, University of Maryland-Baltimore
4:30 – 4:45 p.m. Student Presentation: “The Non-oxidative branch of the pentose phosphate pathway contributes to antioxidative and antinitrosative defenses in Salmonella” – Jeff Shaw, Creighton University

4:45 – 7 p.m.  Happy Hour, Networking, Posters Presentations

June 14, 2018 (Thursday)

7 – 8 a.m. Networking and Coffee

Session 4. Dumpster Diving – Metabolic adaptation by pathogens
8 – 8:30 a.m. Plenary Presentation: “Characterizing the Chemotypic Landscape of Polymicrobial Communities” – Vanessa Phelan, PhD, University of Colorado-Denver
8:30 – 8:50 a.m. Abstract Selected Presentation: “Quantifying the effect of fumarate on central carbon metabolism in Plasmodium falciparum” – Shivenda Tewari, PhD, Department of Defense Biotechnology High Performance Computing Software Applications Institute
8:50 – 9:10 a.m. Abstract Selected Presentation: “Cholesterol-rich microdomains in Borrelia burgdorferi” – Alvaro Toledo, PhD, Rutgers, The State University of New Jersey
9:10 – 9:40 a.m. Plenary Presentation: “The role of mosquito eicosanoids on antiplasmodial defense and immune priming” – Carolina Barillas Mury, MD, PhD, National Institutes of Allergy and Infectious Diseases

9:40 – 10:10 a.m. Morning coffee break

Session 5. Bytes and Goodies – Technologies that drive infectious disease metabolism research
10:10 – 10:40 a.m. Plenary Presentation: “Utilizing LC-MS/MS to interrogate mechanisms of viral metabolic manipulation and vulnerability” – Joshua C. Munger, PhD, University of Rochester Medical Center
10:40 – 11 a.m. Abstract Selected Presentation: “Visualizing the role of cholesterol metabolism in statin-mediated protection against bacterial infection” – Alison Scott, PhD, University of Maryland Baltimore
11 – 11:20 a.m. Abstract Selected Presentation: “Using machine learning tools to identify discriminating metabolites in viral respiratory infection” – Manuchehr Aminian, PhD, Colorado State University
11:20 – 11:50 a.m. Plenary Presentation: “Location, location, location: therapeutic vulnerabilities of compartmentalized metabolism” – Gary Patti, PhD, Washington University

11:50 a.m. – 1:20 p.m. Lunch (Lory Student Center Ballroom C)

Session 6. Just Passing Through…Maybe – Metabolism that promotes disease transmission and persistence
1:20 – 1:50 p.m. Plenary Presentation: “Mapping the trajectory of an infection through metabolic space” – David Schneider,PhD, Stanford University
1:50 – 2:20 p.m. Plenary Presentation: “Multi-omics modeling of Human Immunology – Finding the right Chemistry between Genes” – Shuzhao Li, PhD Emory University
2:20 – 2:40 p.m. Abstract Selected Presentation: “Identification of biochemical choke points to limit dengue, Zika and Chikungunya virus infection in the midgut of the Aedes aegypti mosquito vector” – Nunya Chotiwan, Colorado State University
2:40 – 3:00 p.m. Abstract Selected Presentation: “The effect of physiological state on Powassan virus infection of salivary gland cultures from female Ixodes scapularis (black-legged tick): a potential role for pantothenate and CoA biosynthesis” – Jeffrey Grabowski, PhD, Rocky Mountain Laboratories, NIH
3 – 3:30 p.m. Plenary Presentation: “Exploring bacterial metabolites as drivers of disease phenotypes and co-morbidity in HIV infected individuals” – Catherine Lozupone, PhD, University of Colorado-Denver

3:30 – 4 p.m. Afternoon coffee break

Session 7. State-of-Metabolism in Infectious Diseases
4 – 4:45 p.m. Round Table Discussion – Metabolism of Infectious Diseases – Future Challenges and Directions
4:45 – 5 p.m. Awards for Student Presentations and Posters
5 – 5:15 p.m. Closing remarks

6 – 10 p.m. Gala Dinner at the Rio Grande Mexican Restaurant (143 West Mountain Avenue, Old Town Fort Collins)